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WG2: Pharmacological regulation and drugs

Activities

This WG will coordinate all aspects along the pipeline of drug development, including preclinical studies. All the knowledge gathered and tools developed in WG1 will serve to guide the identification of existing and new compounds that target NRF2 and influence the course of selected NCDs in cellular and animal models. WG2 will strive for standardizing procedures and protocols to maximize the reproducibility of results, and for selecting accurate disease animal models.

Task

  • Inventory of drugs suitable for repurposing in NRF2 therapeutics
  • Inventory of new patented or patentable compounds that target NRF2 and influence the course of various NCDs in cellular and animal models of disease
  • Coordinate a virtual repository of superior animal models for various NCDs with pathophysiological processes related to NRF2 deregulation
  • Critical analysis of preclinical results on the above mentioned NRF2-modulators in superior animal models.

Members

Agnes S. Klar

  • University Children's Hospital Zurich
  • Switzerland (CH)
  • Website

Ahmet Can Timucin

  • Acibadem Mehmet Ali Aydınlar University
  • Turkey (TR)

Ana Casas Guijarro

  • MAASTRICHT UNIVERSITY
  • Netherlands (NL)
  • Website

Ana Cipak Gasparovic

  • Institute Rudjer Boskovic
  • Croatia (HR)
  • Website

Andreas Daiber

  • University Medical Center of the Johannes Gutenberg University Mainz
  • Germany (DE)

Ángel Juan García Yagüe

  • instituto de Investigaciones Biomédicas (Madrid)
  • Spain (ES)

Anton Terasmaa

  • National Institute of Chemical Physics and Biophysics
  • Estonia (EE)

Bilge Debelec Butuner

  • Ege University
  • Turkey (TR)
  • Website

Biljana Miova

  • Faculty of Natural Sciences and Mathematics| University Ss Cyrilus and Methodius| Skopje
  • North Macedonia (MK)

Bruno Ramos-Molina

  • Biomedical Research Institute of Murcia (IMIB-Arrixaca)
  • Spain (ES)

Camillo Rosano

  • IRCCS AOU San Martino - IST National Institute for Cancer Research
  • Italy (IT)

Catalina Anca Cucos

  • Victor Babes National Institute of Pathology (INCDVB)
  • Romania (RO)

Chakradhara Rao S Uppugunduri

  • University of Geneva
  • Switzerland (CH)

Claudia Santos

  • NOVA Medical School
  • Portugal (PT)
  • Website

Diego Lastra

  • Instituto de Investigaciones Biomédicas Alberto Sols
  • Spain (ES)
  • Website

DJORDJE MILJKOVIC

  • Institute for Biological Research "Siniša Stanković" - National Institute of Republic of Serbia| University of Belgrade
  • Serbia (RS)

Efrosyni Paraskeva

  • University of Thessaly
  • Greece (EL)
  • Website

Elena Rafailovska

  • Faculty of Natural Sciences and Mathematics
  • North Macedonia (MK)
  • Website

Eugenia Carvalho

  • Center for Neuroscience and Cell Biology
  • Portugal (PT)

Eva Cano

  • Instituto de Salud Carlos III. Chronic Disease Programme
  • Spain (ES)

George Spyrou

  • The Cyprus Institute of Neurology and Genetics
  • Cyprus (CY)

Gerasimos Sykiotis

  • Lausanne University Hospital
  • Switzerland (CH)

Gina Manda

  • Victor Babes National Institute of Pathology
  • Romania (RO)
  • Website

GUNAY YETIK ANACAK

  • Ege University
  • Turkey (TR)
  • Website

Harry van Goor

  • University of Groningen
  • Netherlands (NL)
  • Website

Helena Vieira

  • UCIBIO| NOVA School of Science and Technology| Universidade Nova de Lisboa
  • Portugal (PT)

huseyin Istanbullu

  • izmir katip celebi university faculty of pharmacy
  • Turkey (TR)

Inês V Silva

  • Faculty of Pharmacy, University of Lisbon
  • Portugal (PT)

Ioannis P. Trougakos

  • National & Kapodistrian University of Athens
  • Greece (EL)

Irina Milisav

  • UL Faculty of Medicine
  • Slovenia (SI)
  • Website

Isabel Lastres-Becker

  • Universidad Autónoma de Madrid
  • Spain (ES)

IVANA STOJANOVIC

  • Institute for Biological Research "Sinisa Stankovic"
  • Serbia (RS)
  • Website

Joana Loureiro

  • Faculty of Engineering| University of Porto
  • Portugal (PT)

Joana Miranda

  • Faculty of Pharmacy from the University of Lisbon (FFUL)
  • Portugal (PT)

Joana S. Rodrigues

  • iMed.ULisboa - Research Institute for Medicines
  • Portugal (PT)
  • Website

Jordi Muntané

  • Hospital Universitario "Virgen del Rocío"
  • Spain (ES)

Jose Jimenez Villegas

  • Instituto de Investigaciones Biomédicas
  • Spain (ES)
  • Website

Josep Julve

  • Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
  • Spain (ES)
  • Website

Juan Antonio Moreno

  • IMIBIC| Cordoba University
  • Spain (ES)
  • Website

Juan Carlos Escola Gil

  • Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
  • Spain (ES)

Kari Espolin Fladmark

  • University of Bergen
  • Norway (NO)
  • Website

Kateřina Valentová

  • Institute of Microbiology of the CAS| v.v.i.
  • Czech Republic (CZ)

Katja Kanninen

  • A.I.Virtanen Institute for Molecular Sciences
  • Finland (FI)

Kattri-Liis Eskla

  • Institute of Biomedicine and Translational Medicine
  • Estonia (EE)

Lidija Milkovic

  • Rudjer Boskovic Institute
  • Croatia (HR)
  • Website

Liliya Mihaylova (Vasileva)

  • Center of Plant Systems Biology and Biotechnology
  • Bulgaria (BG)

Mª Luisa Ferrándiz

  • Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM)
  • Spain (ES)

Maria Carmo Pereira

  • Faculdade de Engenharia da Universidade do Porto
  • Portugal (PT)

Maria Teresa Bayo Jimenez

  • Universitätsmedizin Mainz
  • Germany (DE)

Maria Teresa Cruz

  • Center for Neuroscience and Cell Biology
  • Portugal (PT)

Marisa Andreia Carvalho de Freitas

  • Researcher at REQUIMTE/Faculty of Pharmacy of University of Porto
  • Portugal (PT)

Michel-Edwar Mickael

  • philopater Macavious Enskild firma (PM)
  • Egypt (EG)
  • Website

Miguel Seabra

  • CEDOC - Chronic Diseases Research Center| NOVA Medical School / Universidade Nova de Lisboa
  • Portugal (PT)

Miguel Soares

  • Fundação Calouste Gulbenkian - Instituto Gulbenkian de Ciência
  • Portugal (PT)

Milen Georgiev

  • The Stephan Angeloff Institute of Microbiology
  • Bulgaria (BG)

Milica Lazarevic

  • Institute for biological research "Sinisa Stankovic" National Institute of Republic of Serbia
  • Serbia (RS)

Neda Djedovic

  • Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
  • Serbia (RS)

Nesrin Kartal Ozer

  • Marmara University Faculty of Medicine
  • Turkey (TR)
  • Website

Niki Chondrogianni

  • Institute of Chemical Biology
  • Greece (EL)
  • Website

Petek BALLAR KIRMIZIBAYRAK

  • Ege University
  • Turkey (TR)
  • Website

Rafael León

  • Instituto de Química Médica| Consejo Superior de Investigaciones Científicas (CSIC)
  • Spain (ES)

Raquel Fernández Ginés

  • Autonomous University of Madrid
  • Spain (ES)

Roberta Foresti

  • Institut Mondor de Recherche Biomédicale
  • France (FR)
  • Website

Roberto Motterlini

  • University Paris Est-INSERM U955
  • France (FR)
  • Website

RON KOHEN

  • The Hebrew University of Jerusalem
  • Israel (IL)
  • Website

Sandra Tenreiro

  • CEDOC - Chronic Diseases Research Center
  • Portugal (PT)

Sara Zakaria

  • Vem İlaç San. ve Tic. A.Ş.
  • Turkey (TR)
  • Website

Sibel Kalyoncu Uzunlar

  • Izmir Biomedicine and Genome Center
  • Turkey (TR)

Silvia Giordani

  • Dublin City University
  • Ireland (IE)
  • Website

Srdjan Bjedov

  • Faculty of Sciences – University of Novi Sad
  • Serbia (RS)

Susana Cadenas

  • Centro de Biología Molecular Severo Ochoa (CSIC/UAM)
  • Spain (ES)

Suzana Stanisavljevic

  • Institute for Biological Research "Siniša Stanković"
  • Serbia (RS)

Tilman Grune

  • Deutsches Institut fuer Ernaehrungsforschung Potsdam-Rehbruecke
  • Germany (DE)

Tuğba BOYUNEGMEZ TUMER

  • Canakkale Onsekiz Mart University
  • Turkey (TR)

Ugne Jonavice

  • State Research Institute Centre for Innovative Medicine
  • Lithuania (LT)
  • Website

Vasco Branco

  • Faculdade de Farmácia da Universidade de Lisboa
  • Portugal (PT)

Vera Marisa Costa

  • Toxicology Lab| Faculty of Pharmacy UP
  • Portugal (PT)

Yahya Sohrabi

  • Dept. of Cardiology I – Coronary and Peripheral Vascular Disease
  • Germany (DE)

Zorica Stojic-Vukanic

  • Faculty of Pharmacy
  • Serbia (RS)
  • Website

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COST

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

BenBedPhar CA20121

Action details

Grant Holder: Universidad Autónoma de Madrid
Start of Action: 19 October, 2021
End of Action: 18 October, 2025
CSO approval date: 25 May 2021
Action email: info@benbedphar.org

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