WG1: Tools for NRF2 research
Activities
This WG will critically revise basic mechanisms of NRF2 regulation in health and disease from a systems biology perspective, and coordinate the access of the Action members to databases, standard procedures, state-of-the-art technologies and repositories containing high quality customized reagents, validated animal models and biological samples for NRF2 research.
Task
- Elaboration of guidelines with standardized procedures and protocols, and support for data processing and integration
- Organize a toolbox with customized reagents (cells, antibodies, NRF2 modulators, etc.) for advanced studies on the physiopathological function of NRF2.
- Coordinate access to several biobanks which may provide biologic samples from patients with NRF2-related NCDs and matched controls, in compliance with local ethics regulations
- Create a technologic platform based on the technologies and research tools available in the network, including advanced bioinformatics tools for data analysis from the perspective of systems medicine, machine learning and network pharmacology.
Members
Virginijus Tunaitis
- State Research Institute Centre for Innovative Medicine
- Lithuania (LT)
- Website
