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WG1: Tools for NRF2 research

Activities

This WG will critically revise basic mechanisms of NRF2 regulation in health and disease from a systems biology perspective, and coordinate the access of the Action members to databases, standard procedures, state-of-the-art technologies and repositories containing high quality customized reagents, validated animal models and biological samples for NRF2 research.

Task

  • Elaboration of guidelines with standardized procedures and protocols, and support for data processing and integration
  • Organize a toolbox with customized reagents (cells, antibodies, NRF2 modulators, etc.) for advanced studies on the physiopathological function of NRF2.
  • Coordinate access to several biobanks which may provide biologic samples from patients with NRF2-related NCDs and matched controls, in compliance with local ethics regulations
  • Create a technologic platform based on the technologies and research tools available in the network, including advanced bioinformatics tools for data analysis from the perspective of systems medicine, machine learning and network pharmacology.

Members

A. Suha Yalcin

  • Marmara University School of Medicine
  • Turkey (TR)
  • Website

Agnes S. Klar

  • University Children's Hospital Zurich
  • Switzerland (CH)
  • Website

Alejandro K. Samhan Arias

  • Departamento de Bioquímica e Instituto de Investigaciones Biomédicas Albert Sols
  • Spain (ES)

Aleksandra Piechota-Polańczyk

  • Jagiellonian University
  • Poland (PL)

Ana Cipak Gasparovic

  • Institute Rudjer Boskovic
  • Croatia (HR)
  • Website

Andrea Gažová

  • Andrea Gažová
  • Slovakia (SK)
  • Website

Ángel Juan García Yagüe

  • instituto de Investigaciones Biomédicas (Madrid)
  • Spain (ES)

Anton Terasmaa

  • National Institute of Chemical Physics and Biophysics
  • Estonia (EE)

Arif Kamil Salihoğlu

  • Karadeniz Technical University Faculty of Medicine
  • Turkey (TR)

Arnoud Groen

  • ProteiQ Biosciences GmbH
  • Germany (DE)
  • Website

ASAF MARKO

  • The Hebrew University of Jerusalem
  • Israel (IL)
  • Website

Ayse Kocak Sezgin

  • Kutahya Health Sciences University
  • Turkey (TR)

Brigitte Winklhofer-Roob

  • Karl-Franzens Universität Graz
  • Austria (AT)

Catalina Anca Cucos

  • Victor Babes National Institute of Pathology (INCDVB)
  • Romania (RO)

Christina Morgenstern

  • Medical University of Vienna, Austria
  • Austria (AT)

Diego Lastra

  • Instituto de Investigaciones Biomédicas Alberto Sols
  • Spain (ES)
  • Website

DJORDJE MILJKOVIC

  • Institute for Biological Research "Siniša Stanković" - National Institute of Republic of Serbia| University of Belgrade
  • Serbia (RS)

Efrosyni Paraskeva

  • University of Thessaly
  • Greece (EL)
  • Website

Elena Milanesi

  • Victor Babes National Institute of Pathology
  • Romania (RO)

Eugenia Carvalho

  • Center for Neuroscience and Cell Biology
  • Portugal (PT)

Eva Cano

  • Instituto de Salud Carlos III. Chronic Disease Programme
  • Spain (ES)

George Spyrou

  • The Cyprus Institute of Neurology and Genetics
  • Cyprus (CY)

Gina DeNicola

  • H. Lee Moffitt Cancer Center and Research Institute
  • United States (US)

Harry van Goor

  • University of Groningen
  • Netherlands (NL)
  • Website

Hozumi Motohashi

  • Institute of Developkment| Aging and Cancer
  • Japan (JP)

Ioannis P. Trougakos

  • National & Kapodistrian University of Athens
  • Greece (EL)

Isabel Lastres-Becker

  • Universidad Autónoma de Madrid
  • Spain (ES)

Isabel Varela-Nieto

  • Consejo Superior de Investigaciones Cientificas (CSIC)
  • Spain (ES)

IVANA STOJANOVIC

  • Institute for Biological Research "Sinisa Stankovic"
  • Serbia (RS)
  • Website

Jan Lipov

  • University of Chemistry and Technology Prague
  • Czech Republic (CZ)
  • Website

Juan Antonio Moreno

  • IMIBIC| Cordoba University
  • Spain (ES)
  • Website

Kari Espolin Fladmark

  • University of Bergen
  • Norway (NO)
  • Website

Katja Kanninen

  • A.I.Virtanen Institute for Molecular Sciences
  • Finland (FI)

Kattri-Liis Eskla

  • Institute of Biomedicine and Translational Medicine
  • Estonia (EE)

Lidija Milkovic

  • Rudjer Boskovic Institute
  • Croatia (HR)
  • Website

Maria Carmo Pereira

  • Faculdade de Engenharia da Universidade do Porto
  • Portugal (PT)

Maria J Sanchez Quintero

  • Institute of Biomedical Research in Malaga (IBIMA)
  • Spain (ES)

Maria Teresa Bayo Jimenez

  • Universitätsmedizin Mainz
  • Germany (DE)

Maria Teresa Cruz

  • Center for Neuroscience and Cell Biology
  • Portugal (PT)

Marisa Andreia Carvalho de Freitas

  • Researcher at REQUIMTE/Faculty of Pharmacy of University of Porto
  • Portugal (PT)

Michel-Edwar Mickael

  • philopater Macavious Enskild firma (PM)
  • Egypt (EG)
  • Website

Miguel Soares

  • Fundação Calouste Gulbenkian - Instituto Gulbenkian de Ciência
  • Portugal (PT)

Milica Lazarevic

  • Institute for biological research "Sinisa Stankovic" National Institute of Republic of Serbia
  • Serbia (RS)

Natalija Jonić

  • Institute for Biological Research "Siniša Stanković"
  • Serbia (RS)
  • Website

Neda Djedovic

  • Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
  • Serbia (RS)

Nesrin Kartal Ozer

  • Marmara University Faculty of Medicine
  • Turkey (TR)
  • Website

Raquel Fernández Ginés

  • Autonomous University of Madrid
  • Spain (ES)

Saba Abdulghani

  • Nova Medical School
  • Portugal (PT)
  • Website

Sandra Tenreiro

  • CEDOC - Chronic Diseases Research Center
  • Portugal (PT)

Sara Zakaria

  • Vem İlaç San. ve Tic. A.Ş.
  • Turkey (TR)
  • Website

Susana Cadenas

  • Centro de Biología Molecular Severo Ochoa (CSIC/UAM)
  • Spain (ES)

Suzana Stanisavljevic

  • Institute for Biological Research "Siniša Stanković"
  • Serbia (RS)

Tilman Grune

  • Deutsches Institut fuer Ernaehrungsforschung Potsdam-Rehbruecke
  • Germany (DE)

Ugne Jonavice

  • State Research Institute Centre for Innovative Medicine
  • Lithuania (LT)
  • Website

Vasco Barreto

  • CEDOC- Centro de Estudos de Doenças Crónicas
  • Portugal (PT)

Vera Marisa Costa

  • Toxicology Lab| Faculty of Pharmacy UP
  • Portugal (PT)

Virginijus Tunaitis

  • State Research Institute Centre for Innovative Medicine
  • Lithuania (LT)
  • Website

Yahya Sohrabi

  • Dept. of Cardiology I – Coronary and Peripheral Vascular Disease
  • Germany (DE)