| Cohort owner (Cohort name) | Gothenburg H70 Birth Cohort Studies (Anna Zettergren) |
| Type of recruitment | Population-based longitudinal study of older individuals, recruited from the general population based on birth year and date. |
| Place of recruitment | Gothenburg, Sweden |
| Number of subjects | Approx. 10,000 (but much of the data is only available in sub-groups) |
| F/M | Approx 60% females |
| Age range | 70-110 |
| Healthy/disease (stage?) | Population-based cohorts (baseline age varies between 70 and 95 years of age) |
| Medications y/n | Self-reported information on medication |
| Lifestyle |
| Dietary intake | Diet history interview (data on foods, energy and nutrient intake) |
| Physical activity | yes; interview and self-rating questionnaire (there are also measures of physical function, such as grip strength, gait speed, balance. |
| Biomarkers |
| Body composition | DXA, Antropometric measures |
| Inflammation | CRP (not high sensitive) |
| Vascular/adipose tissue | |
| CV health | NT-proBNP |
| Kidney | Creatinine |
| Liver | AST, ALT |
| Lipid metabolism | Total-, HDL-, LDL-Cholesterol, Triglycerides |
| Glucose metabolism | |
| Protein status | N/A |
| Metabolomics | |
| Iron status | Hemoglobin |
| Vitamin & trace element status | Homocysteine (indirect measure of vit B12) |
| Fatty Acids | |
| AGEs | N/A |
| Glycation | |
| ROS/redox status | |
| Lipidperoxidation | |
| Others (please add) | Genetic data (i.e. GWAS), CSF-biomarkers for Alzheimer´s disease and neurodegeneration (Abeta42, t-tau, p-tau, NfL, Neurogranin), plasma-NfL, Neuroimaging |
| Samples available for further use |
| Plasma/serum | yes |
| Spot urine | N/A |
| 24h urine | N/A |
| Pax tubes (or isolated RNA) | N/A |
| Cells | N/A |
| Tissues | N/A |
| others | |
| Genetics | GWAS |
| Transcription Factors | |
| NRF2/KEAP1 status | |
| redox gene status | |
| CSF Biomarkers | |
| Neuroimaging | Abeta42, t-tau, p-tau, NfL, Neurogranin |
